Human Leukocyte Antigen (HLA) is the expression product of the human major histocompatibility complex and an important genetically encoded product for judging donor-recipient histocompatibility matching in organ transplantation. For various reasons, the donor HLA genotype of some kidney transplant patients is unclear. Based on a next-generation sequencing platform, this test captures and detects donor tissue-derived HLA gene sequences in the urine of kidney transplant recipients, and applies the company's self-developed bioinformatics algorithm model HLA-NIT to analyze the donor organ's HLA genotyping.
Non-invasive detection of donor HLA genotype based on urine DNA