Human Leukocyte Antigen (HLA) is the expression product of the human major histocompatibility complex and is the most important gene-encoded product for determining the histocompatibility match between the donor and recipient in organ transplantation. For various reasons, the donor HLA genotype of some kidney transplant patients is unclear. This test is based on a second-generation gene sequencing platform that captures and detects HLA gene sequences derived from donor tissues in the urine of kidney transplant patients, and uses the company's independently developed bioinformatics algorithm model HLA-NIT to analyze the HLA genotyping of the donor organs.
Non-invasive detection of donor HLA genotype based on urine DNA